Suspense premiered on July 22, 1940, with an episode called "The Lodger." The show aired on a CBS program called Forecast, which premiered the pilot episodes of new series. Although the response to the first episode of Suspense was good, it would be another two years before the series would begin its twenty year run.
The radio-play for "The Lodger" was based on the 1913 novel of the same name by Marie Belloc Lowndes and Alfred Hitchcock's 1927 silent film The Lodger. The premier episode of Suspense is notable primarily because it was directed by Alfred Hitchcock. (For more information about the first show click here.)
Below is a three minute clip of the mob scene from Alfred Hitchcock's The Lodger.
(Video from YouTube.com)